Ischemia/reperfusion injury: A review in relation to free tissue transfers

被引：215
作者：
Siemionow, M [1 ]
Arslan, E [1 ]
机构：
[1] Cleveland Clin Fdn, Dept Plast Surg, Cleveland, OH 44195 USA
来源：
MICROSURGERY | 2004年 / 24卷 / 06期
关键词：
D O I：
10.1002/micr.20060
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Events during ischemia/reperfusion (I/R) injury include: neutrophil-mediated endothelial cytotoxicity and activation, generation of free radicals, triggering of cytokines and chemokines, and activation of adhesion molecules and complement system. This article briefly reviews events occurring during tissue ischemia and reperfusion in relation to free tissue transfers. The consequences of tissue damage at the microcirculatory level are presented. Preventive measures of I/R injury are outlined. (C) 2004 Wiley-Liss, Inc.
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页码：468 / 475
页数：8
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