Pyrroloisoxazoles as a building block for 3-enoyltetramic acids

被引：20

作者：

Jones, RCF ^{[1
]}

Pillainayagam, TA ^{[1
]}

机构：

[1] Univ Loughborough, Dept Chem, Loughborough LE11 3TU, Leics, England

来源：

SYNLETT | 2004年 / 15期

关键词：

acyltetramic acid; isoxazole; cycloaddition; condensation; heterocycle;

D O I：

10.1055/s-2004-835640

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Methylpyrrolo[3,4-c]isoxazoles prepared by nitrile oxide cycloaddition, are deprotonated and condensed with aromatic aldehydes; N-O bond cleavage with Mo(CO)(6) affords 3-enoyltetramic acids whilst with H-2-catalyst further reduction to 3-acyltetramic acids is observed.

引用

页码：2815 / 2817

页数：3

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