OBSTRUCTIVE SLEEP APNEA AND CENTRAL SEROUS CHORIORETINOPATHY

被引：36

作者：

Brodie, Frank L. ^{[1
]}

Charlson, Emily S. ^{[1
]}

Aleman, Tomas S. ^{[1
]}

Salvo, Rebecca T. ^{[1
]}

Gewaily, Dina Y. ^{[1
]}

Lau, Marisa K. ^{[1
]}

Farren, Neil D. ^{[1
]}

Engelhard, Stephanie B. ^{[1
]}

Pistilli, Maxwell ^{[1
]}

Brucker, Alexander J. ^{[1
]}

机构：

[1] Univ Penn, Scheie Eye Inst, Dept Ophthalmol, Philadelphia, PA 19104 USA

来源：

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2015年 / 35卷 / 02期

关键词：

central serous chorioretinopathy; sleep apnea; RISK; DISORDERS; ADULTS;

D O I：

10.1097/IAE.0000000000000326

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: The purpose of this study was to determine if there is an association between obstructive sleep apnea (OSA) and central serous chorioretinopathy (CSCR). Methods: Patients with CSCR without a history of steroid use or secondary retinal disease were matched based on age/gender/body mass index with control patients and administered the Berlin Questionnaire to assess for OSA risk. Patients were scored "OSA+" if they were at "high risk" on the Berlin Questionnaire or reported a previous OSA diagnosis. Rates of OSA+ were compared between the 2 groups, odds ratio and its 95% confidence interval was calculated using exact conditional logistic regression. Results: Forty-eight qualifying patients with CSCR were identified. There were no statistically significant differences between the CSCR and control groups by age (mean = 55 years), gender (79% male), body mass index (mean = 28.2), history of diabetes, or hypertension. Within the CSCR group, 22 patients (45.8%) were OSA+ versus 21 control patients (43.8%) (difference = 2.1%; 95% confidence interval, -18.2% to 22.2%; exact odds ratio = 1.08, 95% confidence interval, 0.47-2.49; P = 1.00). Conclusion: When compared with matched controls, patients with CSCR did not have statistically significant higher rates of OSA risk or previous diagnosis. This finding contrasts with previous work showing a strong association between the diseases. The divergence is likely due to our matching controls for body mass index, a significant risk factor for OSA.

引用

页码：238 / 243

页数：6