High-sensitivity C-reactive protein in every chart? The use of biomarkers in individual patients

被引:16
作者
Ben-Yehuda, Ori [1 ]
机构
[1] Univ Calif San Diego, Med Ctr, Dept Med, San Diego, CA 92103 USA
关键词
D O I
10.1016/j.jacc.2007.04.007
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The use of high-sensitivity C-reactive protein (hsCRP) for risk stratification for cardiovascular disease is supported by epidemiologic evidence but remains controversial. The metabolic milieu in which hsCRP is likely to be elevated, namely abdominal obesity and insulin resistance, provides a framework for the understanding of the role of hsCRP as well its limitations. This commentary provides a critical assessment of the data in support of the use of hsCRP in clinical practice.
引用
收藏
页码:2139 / 2141
页数:3
相关论文
共 15 条
  • [1] A big fat wedding - Association of adiponectin with coronary vascular lesions - Editorial comment
    Bajaj, Mandeep
    Ben-Yehuda, Ori
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (06) : 1163 - 1165
  • [2] Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S
    Ballantyne, CM
    Olsson, AG
    Cook, TJ
    Mercuri, MF
    Pedersen, TR
    Kjekshus, J
    [J]. CIRCULATION, 2001, 104 (25) : 3046 - 3051
  • [3] Which white blood cell subtypes predict increased cardiovascular risk?
    Horne, BD
    Anderson, JL
    John, JM
    Weaver, A
    Bair, TL
    Jensen, KR
    Renlund, DG
    Muhlestein, JB
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (10) : 1638 - 1643
  • [4] Relationship between C-reactive protein and subclinical atherosclerosis - The Dallas Heart Study
    Khera, A
    de Lemos, JA
    Peshock, RM
    Lo, HS
    Stanek, HG
    Murphy, SA
    Wians, FH
    Grundy, SM
    McGuire, DK
    [J]. CIRCULATION, 2006, 113 (01) : 38 - 43
  • [5] Race and gender differences in C-reactive protein levels
    Khera, A
    McGuire, DK
    Murphy, SA
    Stanek, HG
    Das, SR
    Vongpatanasin, W
    Wians, FH
    Grundy, SM
    de Lemos, JA
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (03) : 464 - 469
  • [6] KILNAY S, 2007, J AM COLL CARDIOL, V49, P2003
  • [7] Dietary and genetic probes of atherogenic dyslipidemia
    Krauss, RM
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2005, 25 (11) : 2265 - 2272
  • [8] Elevated C-reactive protein -: Another component of the atherothrombotic profile of abdominal obesity
    Lemieux, I
    Pascot, A
    Prud'homme, D
    Alméras, N
    Bogaty, P
    Nadeau, A
    Bergeron, J
    Després, JP
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (06) : 961 - 967
  • [9] C-Reactive protein and the prediction of cardiovascular events among those at intermediate risk - Moving an inflammatory hypothesis toward consensus
    Ridker, Paul M.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 49 (21) : 2129 - 2138
  • [10] C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events
    Ridker, PM
    Buring, JE
    Cook, NR
    Rifai, N
    [J]. CIRCULATION, 2003, 107 (03) : 391 - 397