Artemisinins: activities and actions

被引:85
作者
Haynes, RK
Krishna, S
机构
[1] St George Hosp, Sch Med, Dept Cellular & Mol Med Infect Dis, London SW17 0RE, England
[2] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
关键词
malaria; artemisinin; multidrug-resistance;
D O I
10.1016/j.micinf.2004.09.002
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Multidrug-resistant malaria caused by Plasmodium falciparum has severely limited treatment options over recent years. Artemisinins are still effective for treating uncomplicated as well as severe malaria, because resistance is not yet clinically apparent. This article reviews some clinically useful properties of artemisinins and how they might work. (C) 2004 Elsevier SAS. All rights reserved.
引用
收藏
页码:1339 / 1346
页数:8
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