New aspects in vascular gene therapy

被引:20
作者
Karvinen, Henna
Yla-Herttuala, Seppo
机构
[1] Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland
基金
芬兰科学院;
关键词
ENDOTHELIAL GROWTH-FACTOR; AAV VECTORS; ANGIOGENESIS; VEGF; MYOCARDIUM; DISEASE; ARTERIOGENESIS; ISCHEMIA; DELIVERY; SAFETY;
D O I
10.1016/j.coph.2010.01.004
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Advances in clinical gene therapy have been modest although significant progress has been made during the past few years. New viruses have been introduced and new results have been collected from preclinical and clinical studies. This review will focus on cardiovascular and especially proangiogenic gene therapy. Recent results from preclinical developments and clinical trials will be discussed.
引用
收藏
页码:208 / 211
页数:4
相关论文
共 50 条
  • [11] Gene therapy for peripheral vascular disease
    Baumgartner, I
    Isner, JM
    ISRAEL MEDICAL ASSOCIATION JOURNAL, 2000, 2 (01): : 27 - 32
  • [12] Vascular Therapy for Radiation Cystitis
    Soler, Roberto
    Vianello, Alberto
    Fuellhase, Claudius
    Wang, Zhan
    Atala, Anthony
    Soker, Shay
    Yoo, James J.
    Williams, James Koudy
    NEUROUROLOGY AND URODYNAMICS, 2011, 30 (03) : 428 - 434
  • [13] Gene therapy with angiogenic factors: A new potential approach to the treatment of ischemic diseases
    Safi, J
    Gloe, TR
    Riccioni, T
    Kovesdi, I
    Capogrossi, MC
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1997, 29 (09) : 2311 - 2325
  • [14] Role of the Oxygen-Dependent Degradation Domain in a Hypoxia-Inducible Gene Expression System in Vascular Endothelial Growth Factor Gene Therapy
    Jin, HongLian
    Liu, Meng-Lu
    Kim, Hyun Ah
    Lee, Minhyung
    An, SungSu
    Oh, JinSoo
    Cho, Joon
    Yi, Seong
    Kim, KeungNyun
    Yoon, DoHeum
    Ha, Yoon
    SPINE, 2009, 34 (26) : E952 - E958
  • [15] Pleiotrophin Gene Therapy for Peripheral Ischemia: Evaluation of Full-Length and Truncated Gene Variants
    Fang, Qizhi
    Mok, Pamela Y.
    Thomas, Anila E.
    Haddad, Daniel J.
    Saini, Shereen A.
    Clifford, Brian T.
    Kapasi, Neel K.
    Danforth, Olivia M.
    Usui, Minako
    Ye, Weisheng
    Luu, Emmy
    Sharma, Rikki
    Bartel, Maya J.
    Pathmanabhan, Jeremy A.
    Ang, Andrew A. S.
    Sievers, Richard E.
    Lee, Randall J.
    Springer, Matthew L.
    PLOS ONE, 2013, 8 (04):
  • [16] NEW TOOLS IN REGENERATIVE MEDICINE: Gene Therapy
    Munoz Ruiz, Miguel
    Regueiro, Jose R.
    STEM CELL TRANSPLANTATION, 2012, 741 : 254 - 275
  • [17] Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke
    Rust, Ruslan
    Gronnert, Lisa
    Gantner, Christina
    Enzler, Alinda
    Mulders, Geertje
    Weber, Rebecca Z.
    Siewert, Arthur
    Limasale, Yanuar D. P.
    Meinhardt, Andrea
    Maurer, Michael A.
    Sartori, Andrea M.
    Hofer, Anna-Sophie
    Werner, Carsten
    Schwab, Martin E.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (28) : 14270 - 14279
  • [18] Combination Therapy Is the New Gene Therapy?
    Ronzitti, Giuseppe
    Mingozzi, Federico
    MOLECULAR THERAPY, 2018, 26 (01) : 12 - 14
  • [19] An update on angiogenic gene therapy:: Vascular endothelial growth factor and other directions
    Yla-Herttuala, Seppo
    CURRENT OPINION IN MOLECULAR THERAPEUTICS, 2006, 8 (04) : 295 - 300
  • [20] Safety and biodistribution of XC001 (encoberminogene rezmadenovec) gene therapy in rats: a potential therapy for cardiovascular diseases
    Stewart, Duncan J.
    Gianchetti, Albert
    Byrnes, Dawn
    Dittrich, Howard C.
    Thorne, Barb
    Manza, Linda L.
    Reinhardt, Rickey R.
    GENE THERAPY, 2024, 31 (1-2) : 45 - 55