Obituary: Dan S Tawfik (1955-2021)

被引：2

作者：

Aharoni, Amir ^{[1
]}

Fleishman, Sarel J. ^{[2
]}

机构：

[1] Ben Gurion Univ Negev, Dept Life Sci, IL-84105 Beer Sheva, Israel

[2] Weizmann Inst Sci, Dept Biomol Sci, IL-7610001 Rehovot, Israel

来源：

FEBS JOURNAL | 2021年 / 288卷 / 13期

关键词：

DIRECTED EVOLUTION; PROTEIN; DESIGN; PHOSPHOTRIESTERASE; EMERGENCE; LINK;

D O I：

10.1111/febs.16019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3880 / 3883

页数：4

共 32 条

[1] Reconstructing a Missing Link in the Evolution of a Recently Diverged Phosphotriesterase by Active-Site Loop Remodeling [J].

Afriat-Jurnou, Livnat ;

Jackson, Colin J. ;

Tawfik, Dan S. .

BIOCHEMISTRY, 2012, 51 (31) :6047-6055

[2] The 'evolvability' of promiscuous protein functions [J].

Aharoni, A ;

Gaidukov, L ;

Khersonsky, O ;

Gould, SM ;

Roodveldt, C ;

Tawfik, DS .

NATURE GENETICS, 2005, 37 (01) :73-76

[3] Innovation by Evolution: Bringing New Chemistry to Life (Nobel Lecture) [J].

Arnold, Frances H. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 58 (41) :14420-14426

[4] Principles for computational design of binding antibodies [J].

Baran, Dror ;

Pszolla, M. Gabriele ;

Lapidoth, Gideon D. ;

Norn, Christoffer ;

Dym, Orly ;

Unger, Tamar ;

Albeck, Shira ;

Tyka, Michael D. ;

Fleishman, Sarel J. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (41) :10900-10905

[5] Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein [J].

Bershtein, Shimon ;

Segal, Michal ;

Bekerman, Roy ;

Tokuriki, Nobuhiko ;

Tawfik, Dan S. .

NATURE, 2006, 444 (7121) :929-932

[6] One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen [J].

Campeotto, Ivan ;

Goldenzweig, Adi ;

Davey, Jack ;

Barfod, Lea ;

Marshall, Jennifer M. ;

Silk, Sarah E. ;

Wright, Katherine E. ;

Draper, Simon J. ;

Higgins, Matthew K. ;

Fleishman, Sarel J. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (05) :998-1002

[7] Subtle Alterations in PCNA-Partner Interactions Severely Impair DNA Replication and Repair [J].

Fridman, Yearit ;

Palgi, Niv ;

Dovrat, Daniel ;

Ben-Aroya, Shay ;

Hieter, Philip ;

Aharoni, Amir .

PLOS BIOLOGY, 2010, 8 (10)

[8] Principles of Protein Stability and Their Application in Computational Design [J].

Goldenzweig, Adi ;

Fleishman, Sarel J. .

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 87, 2018, 87 :105-129

[9] Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability [J].

Goldenzweig, Adi ;

Goldsmith, Moshe ;

Hill, Shannon E. ;

Gertman, Or ;

Laurino, Paola ;

Ashani, Yacov ;

Dym, Orly ;

Unger, Tamar ;

Albeck, Shira ;

Prilusky, Jaime ;

Lieberman, Raquel L. ;

Aharoni, Amir ;

Silman, Israel ;

Sussman, Joel L. ;

Tawfik, Dan S. ;

Fleishman, Sarel J. .

MOLECULAR CELL, 2016, 63 (02) :337-346

[10] Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers [J].

Goldsmith, Moshe ;

Aggarwal, Nidhi ;

Ashani, Yacov ;

Jubran, Halim ;

Greisen, Per Jr. ;

Ovchinnikov, Sergey ;

Leader, Haim ;

Baker, David ;

Sussman, Joel L. ;

Goldenzweig, Adi ;

Fleishman, Sarel J. ;

Tawfik, Dan S. .

PROTEIN ENGINEERING DESIGN & SELECTION, 2017, 30 (04) :333-345

← 1 2 3 4 →