Science's Response to CoVID-19

被引：12

作者：

Long, Marcus J. C. ^{[2
]}

Aye, Yimon ^{[1
]}

机构：

[1] Swiss Fed Inst Technol Lausanne EPFL, CH-1015 Lausanne, Switzerland

[2] Univ Lausanne, CH-1015 Lausanne, Switzerland

来源：

CHEMMEDCHEM | 2021年 / 16卷 / 15期

关键词：

NUCLEIC-ACID DETECTION; DISEASE; 2019; COVID-19; SARS-CORONAVIRUS; DRUG DISCOVERY; CORTICOSTEROID TREATMENT; CRYSTAL-STRUCTURE; MOLECULAR-BASIS; SARS-COV-2; INHIBITORS; VIRUS;

D O I：

10.1002/cmdc.202100079

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

CoVID-19 is a multi-symptomatic disease which has made a global impact due to its ability to spread rapidly, and its relatively high mortality rate. Beyond the heroic efforts to develop vaccines, which we do not discuss herein, the response of scientists and clinicians to this complex problem has reflected the need to detect CoVID-19 rapidly, to diagnose patients likely to show adverse symptoms, and to treat severe and critical CoVID-19. Here we aim to encapsulate these varied and sometimes conflicting approaches and the resulting data in terms of chemistry and biology. In the process we highlight emerging concepts, and potential future applications that may arise out of this immense effort.

引用

页码：2288 / 2314

页数：27

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