Biphosphonate-induced radiographic changes in two pediatric patients with rheumatic diseases

被引：8

作者：

Fernandes, JL

Viana, SL ^{[1
]}

Rocha, AL

Ribeiro, MC

Castro, LC

机构：

[1] Clin Radiol Vila Rica, Magnet Resonance Dept, Brasilia, DF, Brazil

[2] Hosp Santa Lucia, Magnet Resonance Dept, Brasilia, DF, Brazil

[3] Hosp Univ Brasilia, Dept Rheumatol, Brasilia, DF, Brazil

来源：

SKELETAL RADIOLOGY | 2004年 / 33卷 / 12期

关键词：

skeleton; biphosphonates; sclerotic bands; radiography;

D O I：

10.1007/s00256-004-0804-8

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Biphosphonates are now being used experimentally in children to increase bone mass, but their long-term effects remain an issue of concern. We report two cases of biphosphonate-induced radiographic changes in children with rheumatic diseases. Our experience supports the view that clinical improvement and radiographic findings after biphosphonate therapy are related to increased bone mineral density, without effects on the inflammatory process itself. Biphosphonates seem to act in rheumatic diseases by reducing bone turnover instead of improving disease activity.

引用

页码：732 / 736

页数：5

共 12 条

[1] Biphosphonates [J].