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Comparison of monocyte with high density lipoprotein cholesterol ratio in dipper and nondipper hypertensive patients
被引:18
作者:
Selcuk, Murat
[1
]
Yildirim, Ersin
[2
]
Saylik, Faysal
[1
]
机构:
[1] Univ Hlth Sci, Van Educ & Res Hosp, Dept Cardiol, Van, Turkey
[2] Univ Hlth Sci, Umraniye Educ & Res Hosp, Dept Cardiol, Istanbul, Turkey
关键词:
dipper hypertension;
HDL-cholesterol;
hypertension;
monocyte count;
nondipper hypertension;
CORONARY-ARTERY-DISEASE;
BLOOD-PRESSURE;
ORGAN DAMAGE;
RISK;
INDIVIDUALS;
PREDICTOR;
SEVERITY;
EVENTS;
D O I:
10.2217/bmm-2019-0062
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 ;
摘要:
Aim: We aimed to compare the monocyte to HDL-cholesterol ratio (MHR) of nondipper hypertension (NDHT) and dipper hypertension patients. Patients & methods: A total of 162 patients were included in the study. Patients were grouped as dipper and nondipper according to 24-h ambulatory blood pressure recordings. Results: The MHR was significantly higher in nondipper hypertension group compared with control (p < 0.001) and dipper hypertension groups (p = 0.03). MHR, hs-CRP and red-cell distribution width (RDW) were independent predictors of nondipper hypertension. Area under the curve was 0.62 (p = 0.034) for MHR and 0.61 (p = 0.012) for hs-CRP in the ROC analysis. Conclusion: MHR has elevated levels in NDHT patients. Increased levels of MHR may evaluate as increased risk of cardiovascular events in NDHT patients.
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页码:1289 / 1296
页数:8
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