Longitudinal assessment of anti-Mullerian hormone after cesarean section and influence of bilateral salpingectomy on ovarian reserve

Objective: This study aimed to compare longitudinal changes in ovarian reserve markers after cesarean section (CS) with and without bilateral salpingectomy (BS). Study design: We prospectively enrolled women >35 weeks' gestation scheduled for CS alone or CS + BS and obtained blood samples for anti-Mullerian hormone prior to surgery and at 3 and 6 months after surgery. At the 3-month visit, we similarly performed transvaginal ultrasound for antral follicle count. Results: We enrolled 50 women; 30 underwent CS only and 20 underwent CS + BS. Although anti-Mullerian hormone level increased over 6 months of follow-up in both groups, no clinically important differences in the geometric mean (interquartile range) (ng/mL) were observed at any timepoint (baseline [0.69 {0.36-1.21} {CS only} vs 0.49 {0.32-2.10} {CS + BS}, p = 0.64]; 3 months [1.35 {0.58-3.13} vs 1.45 {1.04-2.25}, p = 0.79]; and 6 months [1.74 {0.93-4.45} vs 2.60 {1.41-5.10}, p =0.27]). Similarly, we detected no difference in antral follicle count. Conclusion: BS at the time of CS does not have a negative impact on ovarian reserve 6 months after surgery. (C) 2021 Elsevier Inc. All rights reserved.