Cycloadditions of 1-substituted 1,3-butadienes with 4-or 3-substituted 2(1H)-quinolones acting as dienophiles

被引:0
作者
Fujita, R [1 ]
Oikawa, K [1 ]
Yoshisuji, T [1 ]
Okuyama, Y [1 ]
Nakano, H [1 ]
Matsuzaki, H [1 ]
机构
[1] Tohoku Pharmaceut Univ, Aoba Ku, Sendai, Miyagi 9818558, Japan
关键词
4-substituted 2(1H)-quinolone; cycloaddition; phenanthridine; MO calculation; high pressure; electron-withdrawing group;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Cycloadditions of 1,3-butadiene derivatives having an electron-rich group at the I-position with 4- or 3-substituted 2(1H)-quinolones were carried out to give the richly functionalized phenanthridines under both atmospheric and high pressure conditions. Furthermore, the reactivity of 4- or 3-substituted 2(1H)-quinolones acting as a dienophile with 1-substituted dienes was examined using MO calculation.
引用
收藏
页码:295 / 300
页数:6
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