NMDA receptors in the basal ganglia

被引：33

作者：

Ravenscroft, P ^{[1
]}

Brotchie, J ^{[1
]}

机构：

[1] Univ Manchester, Manchester Movement Disorders Lab, Manchester M13 9PT, Lancs, England

来源：

JOURNAL OF ANATOMY | 2000年 / 196卷

关键词：

glutamate receptors; Parkinson's disease; Huntington's disease;

D O I：

10.1046/j.1469-7580.2000.19640577.x

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The basal ganglia consist of several interconnected nuclei located in the telecephalon, diencephalon and mesencephalon that are involved in a variety of motor and non-motor behavioural functions. Glutamate receptors play a major role in neurotransmission within the basal ganglia and are present in all nuclei of the basal ganglia, This review focuses on the contribution of the NMDA class of glutamatergic receptors to various movement disorders whose primary pathology lies within the basal ganglia and discusses how pharmacological manipulation of such receptors may be therapeutically useful.

引用

页码：577 / 585

页数：9

共 83 条

[1] LIGHT MICROSCOPIC ANALYSIS OF GOLGI-IMPREGNATED RAT SUBTHALAMIC NEURONS [J].

AFSHARPOUR, S .

JOURNAL OF COMPARATIVE NEUROLOGY, 1985, 236 (01) :1-13

[2] EXCITATORY AMINO-ACID BINDING-SITES IN THE BASAL GANGLIA OF THE RAT - A QUANTITATIVE AUTORADIOGRAPHIC STUDY [J].

ALBIN, RL ;

MAKOWIEC, RL ;

HOLLINGSWORTH, ZR ;

DURE, LS ;

PENNEY, JB ;

YOUNG, AB .

NEUROSCIENCE, 1992, 46 (01) :35-48

[3] REDUCTION OF STRIATAL DOPAMINERGIC NEUROTRANSMISSION ELEVATES STRIATAL PROENKEPHALIN MESSENGER-RNA [J].

ANGULO, JA ;

DAVIS, LG ;

BURKHART, BA ;

CHRISTOPH, GR .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1986, 130 (03) :341-343

[4] UP-REGULATION OF FOREBRAIN PROENKEPHALIN MESSENGER-RNA SUBSEQUENT TO NMDA RECEPTOR BLOCKADE [J].

ANGULO, JA ;

WATANABE, Y ;

CADET, J ;

LEDOUX, M ;

MCEWEN, BS .

EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION, 1993, 244 (03) :317-318

[5] TRANSSYNAPTIC MODULATION OF STRIATAL ACH RELEASE IN-VIVO BY THE PARAFASCICULAR THALAMIC NUCLEUS [J].

BALDI, G ;

RUSSI, G ;

NANNINI, L ;

VEZZANI, A ;

CONSOLO, S .

EUROPEAN JOURNAL OF NEUROSCIENCE, 1995, 7 (05) :1117-1120

[6] THE THALAMOSTRIATAL PROJECTION IN THE CAT [J].

BECKSTEAD, RM .

JOURNAL OF COMPARATIVE NEUROLOGY, 1984, 223 (03) :313-346

[7] A PROJECTION TO THE STRIATUM FROM THE MEDIAL SUBDIVISION OF THE POSTERIOR GROUP OF THE THALAMUS IN THE CAT [J].

BECKSTEAD, RM .

BRAIN RESEARCH, 1984, 300 (02) :351-356

[8] THE GLUTAMATE-ENRICHED CORTICAL AND THALAMIC INPUT TO NEURONS IN THE SUBTHALAMIC NUCLEUS OF THE RAT - CONVERGENCE WITH GABA-POSITIVE TERMINALS [J].

BEVAN, MD ;

FRANCIS, CM ;

BOLAM, JP .

JOURNAL OF COMPARATIVE NEUROLOGY, 1995, 361 (03) :491-511

[9] Riluzole delayed appearance of parkinsonian motor abnormalities in a chronic MPTP monkey model [J].

Bezard, E ;

Stutzmann, JM ;

Imbert, C ;

Boraud, T ;

Boireau, A ;

Gross, CE .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1998, 356 (2-3) :101-104

[10]

Blanchet PJ, 1999, J PHARMACOL EXP THER, V290, P1034

← 1 2 3 4 5 6 7 8 9 →