We consider the Cauchy problem for an attraction-repulsion chemotaxis system in Rn with the chemotactic coefficients of the attractant beta(1) and the repellent beta(2). In particular, these coefficients are important role in the global existence and blow up of the solutions. In this paper, we show the local well-posedness of solutions in the critical spaces L-n/2(R-n) and the finite time blow-up of the solution under the condition beta(1) > beta(2) in higher dimensional spaces. (c) 2022 The Authors. Published by Elsevier Inc.