Perspective on the clinical application of troponin in heart failure and states of cardiac injury

被引：17

作者：

Bass, Almasa ^{[2
]}

Patterson, J. Herbert ^{[2
]}

Adams, Kirkwood F., Jr. ^{[1
]}

机构：

[1] UNC Heart Failure Program, Dept Med & Radiol, Chapel Hill, NC 27514 USA

[2] UNC Heart Failure Program, Sch Pharm, Chapel Hill, NC 27514 USA

来源：

HEART FAILURE REVIEWS | 2010年 / 15卷 / 04期

关键词：

Troponin; Biomarker; Heart failure; Prognosis; BRAIN NATRIURETIC PEPTIDE; LEFT-VENTRICULAR DYSFUNCTION; RISK STRATIFICATION; PROGNOSTIC VALUE; MYOCARDIAL-INFARCTION; BIOCHEMICAL MARKERS; CARDIOVASCULAR MORTALITY; INDUCED CARDIOTOXICITY; UNIVERSAL DEFINITION; EUROPEAN-SOCIETY;

D O I：

10.1007/s10741-008-9124-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The ability to measure the appearance of cardiac specific forms of troponin in the blood represents a major advance in the clinical assessment of patients with many types of cardiovascular disease, especially acute coronary syndromes. In this review we focus on the utility of troponin in heart failure where this biomarker has emerged as an independent predictor of prognosis providing information beyond clinical assessment and measurement of b-type natriuretic peptides. The novel clinical role of troponin in a variety of states associated with myocardial injury, including chemotherapy and patients with cardiovascular risk factors, is discussed.

引用

页码：305 / 317

页数：13

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