A label-free electrochemical sensor for detection of mercury(II) ions based on lthe direct growth of guanine nanowire

被引：19

作者：

Huang, Yan Li ^{[1
]}

Gao, Zhong Feng ^{[1
]}

Jia, Jing ^{[1
]}

Luo, Hong Qun ^{[1
]}

Li, Nian Bing ^{[1
]}

机构：

[1] Southwest Univ, Lab Ecoenvironm Three Gorges Reservoir Reg, Sch Chem & Chem Engn, Minist Engn, Chongqing 400715, Peoples R China

来源：

JOURNAL OF HAZARDOUS MATERIALS | 2016年 / 308卷

基金：

中国国家自然科学基金;

关键词：

Guanine nanowire; Hg2+; Electrochemical sensor; G-QUADRUPLEX; HG2+ ION; G-WIRE; DNA; SPECTROMETRY; BIOSENSOR;

D O I：

10.1016/j.jhazmat.2016.01.048

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

A simple, sensitive and label-free electrochemical sensor is developed for detection of Hg2+ based on the strong and stable T-Hg2+-T mismatches. In the presence of Mg2+, the parallel G-quadruplex structures could be specifically recognized and precipitated in parallel conformation. Therefore, the guanine nanowire was generated on the electrode surface, triggering the electrochemical H2O2-mediated oxidation of 3,3',5,5'-tetramethylbenzidine (TMB). In this research, a new method of signal amplification for the quantitative detection of Hg2+ was described based on the direct growth of guanine nanowire via guanine nanowire. Under optimum conditions, Hg2+ was detected in the range of 100 pM-100 nM, and the detection limit is 33 pM. Compared to the traditional single G-quadruplex label unit, this electrochemical sensor showed high sensitivity and selectivity for detecting Hg2+. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：173 / 178

页数：6

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