Bioelectrochemistry, reactive oxygen species, receptors, and cell signaling: how interrelated?

被引：13

作者：

Kovacic, Peter ^{[1
]}

Hall, Marilyn E. ^{[1
]}

机构：

[1] San Diego State Univ, Dept Chem, San Diego, CA 92182 USA

来源：

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION | 2010年 / 30卷 / 01期

关键词：

Bioelectrochemistry; radicals; receptors; cell signaling; electron transfer; UNIFYING ELECTROSTATIC MECHANISM; OXIDATIVE STRESS; REPRODUCTIVE TOXICITY; INTEGRATED APPROACH; NITRIC-OXIDE; TRANSDUCTION; PHOSPHATE; ELECTROCHEMISTRY; RADICALS; ARGININE;

D O I：

10.3109/10799890903517939

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Electrochemistry and cell signaling are widely involved in the operation of biochemical systems. This article discusses the relationship of the two, as well as interconnection with a variety of other aspects, such as free radicals, receptors, and stereochemistry. Both endogenous and exogenous agents are involved. The electrochemistry deals with electrostatics, electron transfer, reduction potentials, as well as involvement in membranes, proteins, and neurotransmission. Application of electrostatics is made to cell signaling involving receptor-ligand action, phosphates, sulfates, metal cations, and miscellaneous others. Apparently, energetics play a significant part. Practical and experimental aspects are also addressed.

引用

页码：1 / 9

页数：9

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