Diagnosis of central precocious puberty: Endocrine assessment

被引：0

作者：

Iughetti, L ^{[1
]}

Predieri, B ^{[1
]}

Ferrari, M ^{[1
]}

Gallo, C ^{[1
]}

Livio, L ^{[1
]}

Milioli, S ^{[1
]}

Forese, S ^{[1
]}

Bernasconi, S ^{[1
]}

机构：

[1] Univ Modena & Reggio Emilia, Dept Pediat, I-41100 Modena, Italy

来源：

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | 2000年 / 13卷

关键词：

gonadotropin; estradiol; testosterone; puberty;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The new methods which are currently available have provided substantial help in performing the differential diagnosis of CPP, especially in detecting very early modifications of gonadotropin secretion. Nocturnal sampling is not a practical tool and generates discomfort for patients, and daytime samples do not yet have sufficient sensitivity; thus, determination of LH levels after GnRH stimulation is the most important test. We emphasize that the use of the GnRH agonist test improves the discrimination of the endocrine investigation, making it easier to differentiate CPP from other conditions, such necessary, but its use in isolation is not as thelarche, Determination of sex steroids is recommended.

引用

页码：709 / 715

页数：7

共 29 条

[1] SERUM LUTEINIZING-HORMONE CONCENTRATIONS INCREASE 100-FOLD IN FEMALES FROM 7 YEARS OF AGE TO ADULTHOOD, AS MEASURED BY TIME-RESOLVED IMMUNOFLUOROMETRIC ASSAY [J].

APTER, D ;

CACCIATORE, B ;

ALFTHAN, H ;

STENMAN, UH .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1989, 68 (01) :53-57

[2] LOCAL EXTRAGONADAL ROLES OF ACTIVINS [J].

BILEZIKJIAN, LM ;

VALE, WW .

TRENDS IN ENDOCRINOLOGY AND METABOLISM, 1992, 3 (06) :218-223

[3] RADIOIMMUNOASSAYS OF UNEXTRACTED GONADOTROPINS IN TIMED FRACTIONS OF 24-HOUR URINE - MORNING INCREASE OF GONADOTROPIN EXCRETION, A CIRCADIAN PATTERN IN RELATION TO PUBERTY [J].

BOURGUIGNON, JP ;

VANDERSCHUERENLODEWEYCKX, M ;

REUTER, AM ;

VRINDTSGEVAERT, Y ;

GERARD, A ;

FRANCHIMONT, P .

HORMONE RESEARCH, 1980, 13 (06) :367-384

[4] Diagnostic value of fluorometric assays in the evaluation of precocious puberty [J].

Brito, VN ;

Batista, MC ;

Borges, MF ;

Latronico, AC ;

Kohek, MBF ;

Thirone, ACP ;

Jorge, BH ;

Arnhold, IJP ;

Mendonca, BB .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (10) :3539-3544

[5] LHRH TEST IN THE ASSESSMENT OF PUBERTY IN NORMAL-CHILDREN [J].

CAVALLO, A ;

ZHOU, XH .

HORMONE RESEARCH, 1994, 41 (01) :10-15

[6]

Chappel S C, 1985, Life Sci, V36, P97, DOI 10.1016/0024-3205(85)90087-6

[7] A CLINICALLY USEFUL METHOD FOR DETECTING GONADOTROPINS IN CHILDREN - ASSESSMENT OF LUTEINIZING-HORMONE AND FOLLICLE-STIMULATING-HORMONE FROM URINE AS AN ALTERNATIVE TO SERUM BY ULTRASENSITIVE TIME-RESOLVED IMMUNOFLUOROMETRIC ASSAYS [J].

DEMIR, A ;

ALFTHAN, H ;

STENMAN, UH ;

VOUTILAINEN, R .

PEDIATRIC RESEARCH, 1994, 36 (02) :221-226

[8]

Eckert KL, 1996, PEDIATRICS, V97, P517

[9] URINARY EXCRETION OF GONADOTROPHINS WITH PARTICULAR REFERENCE TO CHILDREN [J].

FITSCHEN, W ;

CLAYTON, BE .

ARCHIVES OF DISEASE IN CHILDHOOD, 1965, 40 (209) :16-&

[10] THE RELATIONSHIP BETWEEN LUTEINIZING-HORMONE AND ESTRADIOL SECRETION IN FEMALE PRECOCIOUS PUBERTY - EVALUATION BY SENSITIVE GONADOTROPIN ASSAYS AND THE LEUPROLIDE STIMULATION TEST [J].

GARIBALDI, LR ;

ACETO, T ;

WEBER, C ;

PANG, SY .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1993, 76 (04) :851-856

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