Immune-mediated vincristine-induced neuropathy: Unlocking therapies

被引：0
作者：
Savelieff, Masha G. [1 ]
Feldman, Eva L. [1 ,2 ]
机构：
[1] Univ Michigan, NeuroNetwork Emerging Therapies, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Neurol, Ann Arbor, MI 48109 USA
来源：
JOURNAL OF EXPERIMENTAL MEDICINE | 2021年 / 218卷 / 05期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1084/jem.20210286
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Vincristine-induced peripheral neuropathy (VIPN) is a prevalent and painful complication in cancer patients that lacks effective treatments. In this issue of JEM, Starobova et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20201452) report that VIPN is driven by innate immune system activation, a discovery that unlocks immunotherapies as potential treatments.
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页数：3
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