Immune-mediated vincristine-induced neuropathy: Unlocking therapies

被引：0
|
作者：
Savelieff, Masha G. [1 ]
Feldman, Eva L. [1 ,2 ]
机构：
[1] Univ Michigan, NeuroNetwork Emerging Therapies, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Neurol, Ann Arbor, MI 48109 USA
来源：
JOURNAL OF EXPERIMENTAL MEDICINE | 2021年 / 218卷 / 05期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1084/jem.20210286
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Vincristine-induced peripheral neuropathy (VIPN) is a prevalent and painful complication in cancer patients that lacks effective treatments. In this issue of JEM, Starobova et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20201452) report that VIPN is driven by innate immune system activation, a discovery that unlocks immunotherapies as potential treatments.
引用
收藏
页数：3
相关论文
共 50 条
  • [31] Magnesium ions and opioid agonists in vincristine-induced neuropathy
    Magdalena Bujalska
    Helena Makulska-Nowak
    Stanisław W. Gumułka
    Pharmacological Reports, 2009, 61 : 1096 - 1104
  • [32] Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy: Progress Continues
    Diouf, Barthelemy
    Evans, William E.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2019, 105 (02) : 315 - 317
  • [33] IMMUNE-MEDIATED POSTSURGICAL NEUROPATHY
    Staff, N. P.
    Engelstad, J. K.
    Dyck, P. J.
    Dyck, P. J. B.
    JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2009, 14 : 138 - 139
  • [34] Immune-Mediated Postsurgical Neuropathy
    Staff, Nathan P.
    Engelstad, JaNean
    Dyck, Peter J.
    Dyck, P. James B.
    ANNALS OF NEUROLOGY, 2009, 66 : S19 - S19
  • [35] Immune-Mediated Therapies in Lymphoma
    Forbes, Sheryl G.
    Mistry, Haleigh E.
    SEMINARS IN ONCOLOGY NURSING, 2019, 35 (05)
  • [36] A Metabolomics Approach for Early Prediction of Vincristine-Induced Peripheral Neuropathy
    Verma, Parul
    Devaraj, Jayachandran
    Skiles, Jodi L.
    Sajdyk, Tammy
    Ho, Richard H.
    Hutchinson, Raymond
    Wells, Elizabeth
    Li, Lang
    Renbarger, Jamie
    Cooper, Bruce
    Ramkrishna, Doraiswami
    SCIENTIFIC REPORTS, 2020, 10 (01) : 9659
  • [37] NETAZEPIDE IS NEUROPROTECTIVE IN A MOUSE MODEL OF VINCRISTINE-INDUCED SENSORY NEUROPATHY
    Bernard, Amandine
    Bourthoumieu, Sylvie
    Boyce, Malcolm
    Rovini, Amandine
    Desmouliere, Alexis
    Richard, Laurence
    Sturtz, Franck
    Danigo, Aurore
    Demiot, Claire
    JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2022, 27 : S17 - S17
  • [38] AXONAL-TRANSPORT DISTURBANCES IN VINCRISTINE-INDUCED PERIPHERAL NEUROPATHY
    GREEN, LS
    DONOSO, JA
    HELLERBETTINGER, IE
    SAMSON, FE
    ANNALS OF NEUROLOGY, 1977, 1 (03) : 255 - 262
  • [39] Pain related behaviour during vincristine-induced neuropathy in rats
    Authier, N
    Coudore, F
    Eschalier, A
    Fialip, J
    NEUROREPORT, 1999, 10 (05) : 965 - 968
  • [40] A Metabolomics Approach for Early Prediction of Vincristine-Induced Peripheral Neuropathy
    Parul Verma
    Jayachandran Devaraj
    Jodi L. Skiles
    Tammy Sajdyk
    Richard H. Ho
    Raymond Hutchinson
    Elizabeth Wells
    Lang Li
    Jamie Renbarger
    Bruce Cooper
    Doraiswami Ramkrishna
    Scientific Reports, 10
12345