Three megastigmane glycosides from the leaves of Pterospermum semisagittatum

被引：34

作者：

Khan, SH

Mosihuzzaman, M

Nahar, N ^{[1
]}

Rashid, MA

Rokeya, B

Ali, L

Khan, AKA

机构：

[1] Univ Dhaka, Dept Chem, Dhaka 1000, Bangladesh

[2] Univ Dhaka, Dept Pharm, Dhaka 1000, Bangladesh

[3] Bangladesh Inst Res & Rehabil Diabet Endocrine &, Res & Acad Div, Dhaka 1000, Bangladesh

来源：

PHARMACEUTICAL BIOLOGY | 2003年 / 41卷 / 07期

关键词：

Pterospermum semisagittatum; megastigmane; antihyperglycemic; ELISA; insulin release;

D O I：

10.1080/13880200308951345

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Pterospermum semisagittatum leaves yielded three megastigmane glycosides (Z)-4-[3'-(beta-D-glucopyranosyloxy) butylidene]-3,5,5-trimethyl-2-cyclohexen-1-one (1), (E)-4[3'-(beta-D-glucopyranosyloxy)butylidene]-3,5,5-trimethyl- 2-cyclohexen-1-one (2) and (E)-4-hydroxy-4-[3'-((3-D-glucopyranosyloxy)butylidene]-3,5,5-trimethyl-2- cyclohexen-l-one (3). Their structures were established by detailed spectroscopic studies. Compound 3 showed a significant insulin releasing effect on rat pancreatic islets.

引用

页码：512 / 515

页数：4