Heparin-induced thrombocytopenia in the cardiovascular patient: diagnostic and treatment guidelines

被引：20
作者：
Gurbuz, AT
Elliott, WG
Zia, AA
机构：
[1] Tucson Med Ctr, Dept Cardiothorac Surg, Tucson, AZ USA
[2] Tucson Med Ctr, Dept Cardiol, Tucson, AZ USA
来源：
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY | 2005年 / 27卷 / 01期
关键词：
heparin; thrombocytopenia; thrombosis;
D O I：
10.1016/j.ejcts.2004.09.021
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Heparin-induced thrombocytopenia/thrombosis is an immunologic reaction to unfractionated heparin characterized by thrombocytopenia, platelet activation and thrombosis. A high index of suspicion is required for timely diagnosis and treatment. Treatment is complex and outcome maybe less then satisfactory. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码：138 / 149
页数：12
相关论文
共 101 条
[1]  
AMIRAL J, 1992, THROMB HAEMOSTASIS, V68, P95
[2]  
Amiral J, 1997, PLATELETS, V8, P68
[3]  
AMIRAL J, 1995, THROMB HAEMOSTASIS, V73, P21
[4]   HEPARIN-INDUCED THROMBOCYTOPENIA AND RECURRENT THROMBOEMBOLISM [J].
ANSELL, J ;
DEYKIN, D .
AMERICAN JOURNAL OF HEMATOLOGY, 1980, 8 (03) :325-332
[5]   HEPARIN-ASSOCIATED THROMBOCYTOPENIA - A COMPARISON OF 3 HEPARIN PREPARATIONS [J].
BELL, WR ;
ROYALL, RM .
NEW ENGLAND JOURNAL OF MEDICINE, 1980, 303 (16) :902-907
[6]  
BELL WR, 1968, LANCET, V1, P490
[7]  
BERRY CN, 1994, THROMB HAEMOSTASIS, V72, P381
[8]   HEPARIN-INDUCED THROMBOCYTOPENIA AND THROMBOSIS - CLINICAL AND LABORATORY STUDIES [J].
BOSHKOV, LK ;
WARKENTIN, TE ;
HAYWARD, CPM ;
ANDREW, M ;
KELTON, JG .
BRITISH JOURNAL OF HAEMATOLOGY, 1993, 84 (02) :322-328
[9]   PLASMAPHERESIS - A THERAPEUTIC OPTION IN THE MANAGEMENT OF HEPARIN-ASSOCIATED THROMBOCYTOPENIA WITH THROMBOSIS [J].
BRADY, J ;
RICCIO, JA ;
YUMEN, OH ;
MAKARY, AZ ;
GREENWOOD, SM .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1991, 96 (03) :394-397
[10]   ARGATROBAN, A SELECTIVE, POTENT THROMBIN INHIBITOR [J].
BUSH, LR .
CARDIOVASCULAR DRUG REVIEWS, 1991, 9 (03) :247-263
12345678910