Metal-Phenolic Encapsulated Mesoporous Silica Nanoparticles for pH-Responsive Drug Delivery and Magnetic Resonance Imaging

被引：11
|
作者：
Chen, Yan [1 ]
Wang, Juan [1 ,2 ]
Liu, Jianhua [3 ]
Lu, Lehui [1 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China
[2] Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China
[3] Jilin Univ, Hosp 2, Dept Radiol, Changchun 130041, Jilin, Peoples R China
来源：
ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS | 2018年 / 232卷 / 9-11期
关键词：
drug delivery; magnetic resonance imaging; mesoporous silica nanoparticles; CONTROLLED-RELEASE; RESISTANT CANCER; SYSTEM; NANOMATERIALS; NETWORKS; CAPSULES; CARRIERS; THERAPY;
D O I：
10.1515/zpch-2018-1145
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The anticancer drug doxorubicin (DOX) is locked in the mesoporous silica nanoparticle by coating Fe-III-TA polymer, and its burst release can be achieved under acidic environment, along with the decreased longitudinal relaxivity. This nanoplatform shows great potential to monitoring the drug delivery process and the fate of the nanocarrier.
引用
收藏
页码：1733 / 1740
页数：8
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