Shell-in-shell microcapsules:: A novel tool for integrated, spatially confined enzymatic reactions

被引：246
作者：
Kreft, Oliver
Prevot, Michelle
Moehwald, Helmuth
Sukhorukov, Gleb B.
机构：
[1] Max Planck Inst Kolloid & Granzflachenforsch, D-14424 Potsdam, Germany
[2] Queen Mary Univ London, Dept Mat, London, England
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 29期
关键词：
materials science; microencapsulation; microreactors; multilayers; polyelectrolytes;
D O I：
10.1002/anie.200701173
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) The Matryoshka theory: This unique type of shell-in-shell microcapsule facilitates the stable spatial separation of biopolymers (enzymes) within distinct compartments of a single capsule entity. Architecture and wall properties of this system allow for the concerted action of enzymes from separate capsule compartments by metabolite diffusion across a semipermeable, intersecting polyelectrolyte membrane. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：5605 / 5608
页数：4
相关论文
共 43 条
[1]   Magnetic microcapsules with low permeable polypyrrole skin layer [J].
Andreeva, Daria V. ;
Gorin, Dmitry A. ;
Shchukin, Dmitry G. ;
Sukhorukov, Gleb B. .
MACROMOLECULAR RAPID COMMUNICATIONS, 2006, 27 (12) :931-936
[2]   Fabrication of a novel type of metallized colloids and hollow capsules [J].
Antipov, AA ;
Sukhorukov, GB ;
Fedutik, YA ;
Hartmann, J ;
Giersig, M ;
Möhwald, H .
LANGMUIR, 2002, 18 (17) :6687-6693
[3]   Loading the multilayer dextran sulfate/protamine microsized capsules with peroxidase [J].
Balabushevich, NG ;
Tiourina, OP ;
Volodkin, DV ;
Larionova, NI ;
Sukhorukov, GB .
BIOMACROMOLECULES, 2003, 4 (05) :1191-1197
[4]   Integrated nanoreactor systems: Triggering the release and mixing of compounds inside single vesicles [J].
Bolinger, PY ;
Stamou, D ;
Vogel, H .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (28) :8594-8595
[5]   Core-referenced ratiometric fluorescent potassium ion sensors using self-assembled ultrathin films on europium nanoparticles [J].
Brown, JQ ;
McShane, MJ .
IEEE SENSORS JOURNAL, 2005, 5 (06) :1197-1205
[6]  
Dai ZF, 2002, ANGEW CHEM INT EDIT, V41, P4019, DOI 10.1002/1521-3773(20021104)41:21<4019::AID-ANIE4019>3.0.CO
[7]  
2-Z
[8]   Intracellularly degradable polyelectrolyte microcapsules [J].
De Geest, BG ;
Vandenbroucke, RE ;
Guenther, AM ;
Sukhorukov, GB ;
Hennink, WE ;
Sanders, NN ;
Demeester, J ;
De Smedt, SC .
ADVANCED MATERIALS, 2006, 18 (08) :1005-+
[9]   Stimuli-responsive multilayered hybrid nanoparticle/polyelectrolyte capsules [J].
De Geest, Bruno G. ;
Skirtach, Andrei G. ;
De Beer, Thomas R. M. ;
Sukhorukov, Gleb B. ;
Bracke, Lieven ;
Baeyens, Willy R. G. ;
Demeester, Joseph ;
De Smedt, Stefaan C. .
MACROMOLECULAR RAPID COMMUNICATIONS, 2007, 28 (01) :88-95
[10]   Fuzzy nanoassemblies: Toward layered polymeric multicomposites [J].
Decher, G .
SCIENCE, 1997, 277 (5330) :1232-1237
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