Is 68Ga-Prostate-Specific Membrane Antigen PET/CT Superior than 18F-FDG PET/CT for Evaluation of Metastatic Osteosarcoma?

被引：8
作者：
Can, Canan [1 ]
Gundogan, Cihan [1 ]
Komek, Halil [1 ]
机构：
[1] Univ Hlth Sci, Dept Nucl Med, Gazi Yasargil Training & Res Hosp, Diyarbakir, Turkey
来源：
CLINICAL NUCLEAR MEDICINE | 2021年 / 46卷 / 04期
关键词：
F-18-FDG; Ga-68-PSMA; osteosarcoma; PET/CT; PSMA; SARCOMA;
D O I：
10.1097/RLU.0000000000003320
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We present the case of a 75-year-old man with osteosarcoma of the sternum in whom Ga-68-prostate-specific membrane antigen (PSMA) PET/CT showed high radiotracer activity in the primary tumor and metastatic lesions than F-18-FDG PET/CT. The present case shows that Ga-68-PSMA PET/CT is very useful for staging of osteosarcoma due to in vivo expression of PSMA. Ga-68-PSMA PET/CT can have potential effects on prognosis and in response assessment following treatment in osteosarcoma. The use of PSMA-targeted radioligand treatments may be beneficial especially in metastatic chemorefractory osteosarcoma.
引用
收藏
页码：E233 / E235
页数：3
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