Clinical significance of lymphoid hyperplasia of the lower gastrointestinal tract

被引：21

作者：

Krauss, E. ^{[1
]}

Konturek, P. ^{[1
]}

Maiss, J. ^{[2
]}

Kressel, J. ^{[1
]}

Schulz, U. ^{[3
]}

Hahn, E. G. ^{[1
]}

Neurath, M. F. ^{[1
]}

Raithel, M. ^{[1
]}

机构：

[1] Univ Erlangen Nurnberg, Dept Med 1, D-91054 Erlangen, Germany

[2] Gastroenterol Clin Dr Kerzel PD Dr Maiss, Forchheim, Germany

[3] Medistat Med Stat, Kronshagen, Germany

来源：

ENDOSCOPY | 2010年 / 42卷 / 04期

关键词：

LYMPHONODULAR HYPERPLASIA; NODULAR HYPERPLASIA; CHILDREN; FOLLICLES; DISORDER; ALLERGY; SYSTEM; COLON;

D O I：

10.1055/s-0029-1243936

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Lymphoid hyperplasia of the intestine has been associated with multiple diseases and symptoms. This study was undertaken to analyze the number and topographical distribution of the lymphoid follicles. A total of 302 adult consecutive patients were enrolled when they underwent elective colonoscopy. Standardized pictures from terminal ileum and colon were taken using video colonoscopes. In each picture, the number, size, and mucosal elevation of lymphoid follicles were analyzed in relation to histological and immunological findings and medical history. Lymphoid hyperplasia was found to be most extensive in the terminal ileum and cecum. Patients with untreated gastrointestinally mediated allergy (GMA) showed the highest number of lymphoid follicles per visible field in the terminal ileum (P < 0.001) and cecum (P = 0.003) vs. the control group. Patients with infectious colitis also showed a high number of lymphoid follicles per endoscopic visible field in the transverse colon (P = 0.020). The presence of lymphoid hyperplasia is a frequent finding during colonoscopy. It may indicate an enhanced immunological mucosal response to antigenic stimulation such as GMA or infection.

引用

页码：334 / 337

页数：4

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