Local Allergic Rhinitis

被引：41

作者：

Campo, Paloma ^{[1
]}

Salas, Maria ^{[1
]}

Blanca-Lopez, Natalia ^{[2
]}

Rondon, Carmen ^{[1
]}

机构：

[1] Reg Univ Hosp Malaga, Plaza Hosp Civil S-N,Pabellon 6, Malaga 29009, Spain

[2] Hosp Infanta Leonor, Allergy Serv, Gran Via Este 80, Madrid 28031, Spain

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2016年 / 36卷 / 02期

关键词：

Local allergic rhinitis; Asthma; Nasal allergen provocation test; Local IgE; Natural evolution; Allergen immunotherapy; NASAL PROVOCATION TEST; PERSISTENT NONALLERGIC RHINITIS; CLASS SWITCH RECOMBINATION; EPSILON-HEAVY-CHAIN; NEGATIVE SKIN-TESTS; IGE ANTIBODIES; DERMATOPHAGOIDES-PTERONYSSINUS; IDIOPATHIC RHINITIS; NONATOPIC ASTHMA; CLINICAL CHARACTERISTICS;

D O I：

10.1016/j.iac.2015.12.008

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

This review focuses on local allergic rhinitis, a new phenotype of allergic rhinitis, commonly misdiagnosed as nonallergic rhinitis. It has gained attention over last decade and can affect patients from all countries, ethnic groups and ages, impairing their quality of life, and is frequently associated with conjunctivitis and asthma. Diagnosis is based on clinical history, the demonstration of a positive response to nasal allergen provocation test and/or the detection of nasal sIgE. A positive basophil activation test may support the diagnosis. Recent studies have demonstrated that allergen immunotherapy is an effective immune-modifying treatment, high-lighting the importance of early diagnosis.

引用

页码：321 / +

页数：14

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