Engineering Static and Dynamic Control of Synthetic Pathways

被引：206

作者：

Holtz, William J. ^{[3
,5
]}

Keasling, Jay D. ^{[1
,2
,4
,5
,6
]}

机构：

[1] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Dept Elect Engn & Comp Sci, Berkeley, CA 94720 USA

[4] Univ Calif Berkeley, Lawrence Berkeley Lab, Phys Biosci Div, Berkeley, CA 94720 USA

[5] Synthet Biol Engn Res Ctr, Emeryville, CA 94608 USA

[6] Joint BioEnergy Inst, Emeryville, CA 94608 USA

来源：

CELL | 2010年 / 140卷 / 01期

关键词：

ESCHERICHIA-COLI; MEVALONATE PATHWAY; MESSENGER-RNA; GENE NETWORKS; OPTIMIZATION; EXPRESSION; BIOSYNTHESIS; METABOLISM; FRAMEWORK; TARGETS;

D O I：

10.1016/j.cell.2009.12.029

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：19 / 23

页数：5

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