Gamma knife stereotactic radiosurgery in recurrent or residual glioblastoma multiforme - our experience in two neurosurgical units

This paper is a retrospective analysis of a 33 patient cohort with diagnosis of glioblastoma multiforme treated using gamma knife stereotactic radiation therapy following surgical resection and fractionated radiation therapy. Over all, 35 stereotactic radiation procedures were performed. Within this group, we differentiated patients who benefited from these procedures - we managed to stabilise or achieve remission of the disease in 13 cases (37%) in a 3 month follow-up and in 6 cases (18%) in a 6-month follow-up. Long-term remission of this highly malignant tumor using gamma knife therapy was achieved in 4 patients.