Fecal microbiota transplantation associated with 10 years of stability in a patient with SPMS

被引：107
作者：
Makkawi, Seraj [1 ,2 ]
Camara-Lemarroy, Carlos [1 ]
Metz, Luanne [1 ]
机构：
[1] Univ Calgary, Cumming Sch Med, Dept Clin Neurosci, Calgary, AB, Canada
[2] King Saud Bin Abdulaziz Univ Hlth Sci, Jeddah, Saudi Arabia
来源：
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION | 2018年 / 5卷 / 04期
关键词：
D O I：
10.1212/NXI.0000000000000459
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Several studies link the gut microbiome and MS immunopathogenesis. Fecal microbiota transplantation (FMT), the process of transferring fecal microbiota from a healthy donor to a patient, successfully treats recurrent Clostridium difficile enterocolitis and may benefit autoimmune diseases. The potential short-term efficacy of this procedure has been reported in MS. Here, we describe a patient with secondary progressive MS (SPMS) who achieved disease stability for over 10 years following FMT. © 2018 American Academy of Neurology.
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