C-arm CT-guided renal arterial embolisation followed by radiofrequency ablation for treatment of patients with unresectable renal cell carcinoma

被引：8

作者：

Duan, X. -H. ^{[1
]}

Li, Y. -S. ^{[2
]}

Han, X. -W. ^{[1
]}

Wang, Y. -L. ^{[1
]}

Jiao, D. -C. ^{[1
]}

Li, T. -F. ^{[1
]}

Chen, P. -F. ^{[1
]}

Fang, Y. ^{[1
]}

机构：

[1] Zhengzhou Univ, Affiliated Hosp 1, Dept Intervent Radiol, 1 East Jian She Rd, Zhengzhou 450052, Henan Province, Peoples R China

[2] Zhengzhou Univ, Affiliated Hosp 1, Dept Urol, 1 East Jian She Rd, Zhengzhou 450052, Henan Province, Peoples R China

来源：

CLINICAL RADIOLOGY | 2016年 / 71卷 / 01期

基金：

中国国家自然科学基金;

关键词：

RADIO-FREQUENCY ABLATION; CONE-BEAM CT; THERMAL ABLATION; HEPATOCELLULAR-CARCINOMA; TUMOR ABLATION; CANCER; MANAGEMENT; SURGERY; LESIONS; SYSTEM;

D O I：

10.1016/j.crad.2015.10.012

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

AIM: To explore the value of using flat detector (FD) equipped angiographic C-arm CT (CACT) systems in treating unresectable renal cell carcinoma (RCC) by selective renal arterial embolisation (RAE) followed by radiofrequency ablation (RFA) (RAE-RFA). MATERIALS AND METHODS: A total of 28 patients who were not candidates for surgery were enrolled. The average size of tumours was 6.7 +/- 2.2 cm (range 4.1-9.6 cm). Twenty-eight tumours were treated with CACT-guided RFA, 5-7 days after CACT-guided RAE. RESULTS: CACT-guided RAE-RFA was technically successful in all patients. Tumour enhancement disappeared after a single RAE-RFA session in 20 patients, after two RAE-RFA sessions in four patients and after three RAE-RFA sessions in the other four patients. One patient died of lung metastasis and haematuria 13 months after RAE-RFA, and another patient died of pulmonary heart disease 23 months after repeat RAE-RFA. In the 26 living patients, tumours remained controlled during a mean follow-up period of 27 months and showed significant reduction in tumour size (6.7 +/- 2.2 cm to 3.9 +/- 1.7 cm, p<0.01). There were no significant changes in creatinine levels or urea nitrogen concentrations before and after the last RAE-RFA (p>0.05). There were no serious complications during and after the procedure. CONCLUSION: CACT-guided RAE followed by RFA appears to be a safe and effective technique for treating patients with inoperable RCC. (C) 2015 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

引用

页码：79 / 85

页数：7

共 24 条

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