Intermittent Fasting versus Continuous Calorie Restriction: Which Is Better for Weight Loss?

被引：24
作者：
Zhang, Qing [1 ]
Zhang, Caishun [1 ]
Wang, Haidan [1 ]
Ma, Zhengye [2 ]
Liu, Defeng [2 ]
Guan, Xiaohan [2 ]
Liu, Yixin [2 ]
Fu, Yanwen [2 ]
Cui, Mingxuan [2 ]
Dong, Jing [1 ,3 ]
机构：
[1] Qingdao Univ, Med Coll, Special Med Dept, Qingdao 266071, Peoples R China
[2] Qingdao Univ, Med Coll, Clin Med Dept, Qingdao 266071, Peoples R China
[3] Qingdao Univ, Med Coll, Physiol Dept, Qingdao 266071, Peoples R China
来源：
NUTRIENTS | 2022年 / 14卷 / 09期
基金：
中国国家自然科学基金;
关键词：
intermittent fasting; calorie restriction; energy control; BMI; body weight; meta-analysis; CONTINUOUS ENERGY RESTRICTION; BODY-MASS INDEX; CARDIOVASCULAR-DISEASE; DIET; HEALTH; METAANALYSIS; METABOLISM; BENEFITS; AGE;
D O I：
10.3390/nu14091781
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
We conducted a systematic review and meta-analysis of randomized clinical trials and pilot trial studies to compare the effectiveness of intermittent fasting (IF) and continuous calorie restriction (CCR) in overweight and obese people. The parameters included body mass index (BMI), body weight, and other metabolism-related indicators. A systematic search in PubMed, Embase, Cochrane Library, and Web of Science was conducted up to January 2022. Standardized mean differences (SMDs) with 95% confidence intervals (CIs) were used to measure the effectiveness. Publication bias was assessed using Egger's test. The stability of the results was evaluated using sensitivity analyses. The significance of body weight change (SMD = -0.21, 95% CI (-0.40, -0.02) p = 0.028) was more significant after IF than CCR. There was no significant difference in BMI (SMD = 0.02, 95% CI (-0.16, 0.20) p = 0.848) between IF and CCR. These findings suggest that IF may be superior to CCR for weight loss in some respects.
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页数：19
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