Synthesis and antibacterial activity of some aryloxy/thioaryloxy oxazolidinone derivatives

被引：18
作者：
Arora, V
Salunkhe, MM
Sinha, N
Sinha, RK
Jain, S
机构：
[1] New Chem Ent Res, Div Med Chem, Pune 411042, Maharashtra, India
[2] New Chem Ent Res, Div Microbiol, Pune 411042, Maharashtra, India
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2004年 / 14卷 / 18期
关键词：
antibacterial; oxazolidinone; aryloxy/thioaryloxy derivatives; resistant bacteria;
D O I：
10.1016/j.bmcl.2004.06.096
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of aryloxy/thioaryloxy oxazolidinone derivatives has been synthesized and tested for in vitro antibacterial activity by MIC determination against a panel of susceptible and resistant Gram-positive and Gram-negative microorganisms, some of which are resistant to methicillin and vancomycin. Compounds 12a, 12b, 14a, and 14b from this series were found to be equipotent or more potent than linezolid in vitro. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4647 / 4650
页数：4
相关论文
共 50 条
[41]   Novel Oxazolidinone Derivatives Containing Quaternary Ammonium Fragments with Potent Antibacterial Potency [J].
Zheng, Chenghong ;
Wang, Minghua ;
Wang, Ying ;
Wang, Xiukun ;
Han, Ying ;
You, Xuefu ;
Hu, Xinxin ;
Zhu, Mei ;
Zhang, Guoning ;
Yu, Liyan ;
Wang, Yucheng ;
Wang, Juxian .
ACS MEDICINAL CHEMISTRY LETTERS, 2025,
[42]   Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity [J].
Maccari, Giorgio ;
Sanfilippo, Stefania ;
De Luca, Filomena ;
Deodato, Davide ;
Casian, Alexandru ;
Lang, Maria Chiara Dasso ;
Zamperini, Claudio ;
Dreassi, Elena ;
Rossolini, Gian Maria ;
Docquier, Jean-Denis ;
Botta, Maurizio .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (23) :5525-5529
[43]   SYNTHESIS AND IN VITRO ANTIBACTERIAL ACTIVITY OF FOUR NOVEL PLEUROMUTILIN DERIVATIVES [J].
Tang, Youzhi ;
Luo, Jian ;
Chen, Xiaojie ;
Wang, Bo ;
Shen, Xiangguang ;
Liu, Jianhua .
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY, 2013, 58 (01) :1537-1540
[44]   Synthesis and antibacterial activity of 1,5-benzothiazepine derivatives [J].
Desai, MD ;
Desai, KK .
ASIAN JOURNAL OF CHEMISTRY, 2002, 14 (02) :974-978
[45]   Synthesis and antibacterial activity of 9-substituted minocycline derivatives [J].
Sum, PE ;
Ross, AT ;
Petersen, PJ ;
Testa, RT .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (02) :400-403
[46]   Synthesis and Antimicrobial Activity of Some Pyrazoline Derivatives [J].
Ahirwar, M. K. ;
Gautam, N. ;
Shrivastava, S. P. .
ASIAN JOURNAL OF CHEMISTRY, 2010, 22 (07) :5297-5302
[47]   The effect of lipophilicity on the antibacterial activity of some 1-benzylbenzimidazole derivatives [J].
Podunavac-Kuzmanovic, S. O. ;
Cvetkovic, D. D. ;
Barna, D. J. .
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2008, 73 (10) :967-978
[48]   Synthesis and Antibacterial Activity of Some New 4(3H)Quinazolin-4-one Derivatives [J].
Azab, M. E. ;
Kassab, E. A. ;
El-Hashash, M. A. ;
Ali, R. S. .
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2009, 184 (03) :610-625
[49]   Synthesis, antibacterial, antifungal and antiviral activity evaluation of some new bis-Schiff bases of isatin and their derivatives [J].
Jarrahpour, Aliasghar ;
Khalili, Dariush ;
De Clercq, Erik ;
Salmi, Chanaz ;
Brunel, Jean Michel .
MOLECULES, 2007, 12 (08) :1720-1730
[50]   SYNTHESIS OF SOME PYRAZOLO (3,4-b) PYRIDINE DERIVATIVES PROVEN EFFECTIVE AS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY [J].
Jadhav, Archana D. ;
Barhate, Pankaj ;
Durrani, Ayesha .
HETEROCYCLIC LETTERS, 2021, 11 (04) :667-673
12345