Capillary electrophoretic enantioseparations using macrocyclic antibiotics as chiral selectors

被引：120

作者：

Armstrong, DW ^{[1
]}

Nair, UB ^{[1
]}

机构：

[1] Univ Missouri, Dept Chem, Rolla, MO 65401 USA

来源：

ELECTROPHORESIS | 1997年 / 18卷 / 12-13期

关键词：

enantiomers; rifamycin B; rifamycin SV; vancomycin; ristocetin; teicoplanin; avoparcin; capillary electrophoresis;

D O I：

10.1002/elps.1150181224

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Macrocyclic antibiotics are the newest class of chiral selector used in capillary electrophoresis (CE) enantioseparations. Two basic types of compounds have proven to produce useful enantioseparations. They are the ansa compounds and the glycopeptides. The ansa compounds best resolve basic or cationic racemates while the glycopeptides best resolve acidic or anionic analytes. The structure and use of these chiral selectors are discussed. The factors affecting separation and the separation mechanism are considered as well.

引用

页码：2331 / 2342

页数：12

共 51 条

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[2]

Arai T, 1996, J CHROMATOGR A, V736, P303

[3]

Armstrong D W., 1994, Pittsburg Conference Abstracts, P572

[4] MACROCYCLIC ANTIBIOTICS AS A NEW CLASS OF CHIRAL SELECTORS FOR LIQUID-CHROMATOGRAPHY [J].