Single all-fiber-based nanosecond-pulsed supercontinuum source for multispectral photoacoustic microscopy and optical coherence tomography

被引：37

作者：

Shu, Xiao ^{[1
]}

Bondu, Magalie ^{[2
,3
]}

Dong, Biqin ^{[1
]}

Podoleanu, Adrian ^{[2
]}

Leick, Lasse ^{[3
]}

Zhang, Hao F. ^{[1
,4
]}

机构：

[1] Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA

[2] Univ Kent, Sch Phys Sci, Appl Opt Grp, Canterbury CT2 7NH, Kent, England

[3] NKT Photon AS, DK-3460 Birkerod, Denmark

[4] Northwestern Univ, Dept Ophthalmol, Chicago, IL 60611 USA

来源：

OPTICS LETTERS | 2016年 / 41卷 / 12期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1364/OL.41.002743

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We report the usefulness of a single all-fiber-based supercontinuum (SC) source for combined photoacoustic microscopy (PAM) and optical coherence tomography (OCT). The SC light is generated by a tapered photonic crystal fiber pumped by a nanosecond pulsed master oscillator power amplifier at 1064 nm. The spectrum is split into a shorter wavelength band (500-800 nm) for single/multi-spectral PAM and a longer wavelength band (800-900 nm) band for OCT. In vivo mouse ear imaging was achieved with an integrated dual-modality system. We further demonstrated its potential for spectroscopic photoacoustic imaging by doing multispectral measurements on retinal pigment epithelium and blood samples with 15-nm line-width. (C) 2016 Optical Society of America

引用

页码：2743 / 2746

页数：4

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