T4b oral cavity cancer below the mandibular notch is resectable with a favorable outcome

被引：79

作者：

Liao, Chun-Ta

Ng, Shu-Hang

Chang, Joseph Tung-Chieh

Wang, Hung-Ming

Hsueh, Chuen

Lee, Li-Yu

Tsao, Chung-Kan

Chen, Wen-Ho

Chen, I-How

Kang, Chung-Jan

Huang, Shiang-Fu

Yen, Tzu-Chen

机构：

[1] Chang Gung Mem Hosp, Dept Nucl Med, Taipei 105, Taiwan

[2] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Dept Otorhinolaryngol Head & Neck Surg, Tao Yuan, Taiwan

[3] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Dept Diagnost Radiol, Tao Yuan, Taiwan

[4] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Dept Internal Med,Div Hematol Oncol, Tao Yuan, Taiwan

[5] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Dept Pathol, Tao Yuan, Taiwan

[6] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Dept Plast & Reconstruct Surg, Tao Yuan, Taiwan

[7] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Dept Oral & Maxillofacial Surg, Tao Yuan, Taiwan

[8] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Dept Nucl Med, Tao Yuan, Taiwan

[9] Chang Gung Univ, Chang Gung Mem Hosp, Coll Med, Mol Imaging Ctr, Tao Yuan, Taiwan

[10] Chang Gung Canc Ctr, Taipei Chang Gung Head & Neck Oncol Grp, Tao Yuan, Taiwan

[11] Chang Gung Univ, Coll Med, Chang Gung Mem Hosp, Dept Radiat Oncol, Tao Yuan, Taiwan

来源：

ORAL ONCOLOGY | 2007年 / 43卷 / 06期

关键词：

squamous cell carcinoma; oral cavity cancer;

D O I：

10.1016/j.oraloncology.2006.06.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

According to the AJCC 2002 staging system, squamous cell carcinoma of the oral cavity (OSCC) with T4b is unresectabte. Herein, we report on our surgical outcome for T4b OSCC. AR patients were enrolled before 2002. From January 1996 to December 2000, 45 consecutive untreated T4b OSCC patients were included. According to the trans-axial plane of the mandibular notch on CT/MRI, seven were supra-notch T4b and 38 were infra-notch T4b tumors. Significantly higher 5-year loco-regional control and survivals were observed in patients with infra-notch T4b than with supra-notch T4b. In the infra-notch group, pN0-1 patients had a significantly higher 5-year loco-regional control and survivals than pN2 patients. Nerve invasion was the sole significant adverse factor for loco-regional control and survivals in the infra-notch T4b group with pN0-1. Our retrospective study demonstrated that OSCC patients of infra-notch T4b with pN0-1 and no nerve invasion might have a favorable surgical outcome. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：570 / 579

页数：10

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