Miliary Tuberculosis in a Young Woman with Hemophagocytic Syndrome: A Case Report and Literature Review

被引:10
作者
Asaji, Mina [1 ]
Tobino, Kazunori [1 ,2 ]
Murakami, Koujin [1 ]
Goto, Yuki [1 ]
Sueyasu, Takuto [1 ]
Nishizawa, Saori [1 ]
Yoshimine, Kohei [1 ]
Munechika, Miyuki [1 ]
Ko, Yuki [1 ]
Yoshimatsu, Yuki [1 ]
Tsuruno, Kosuke [1 ]
Ide, Hiromi [1 ]
Miyajima, Hiroyuki [1 ]
Ebi, Noriyuki [1 ]
机构
[1] Iizuka Hosp, Dept Resp Med, Iizuka, Fukuoka, Japan
[2] Juntendo Univ, Sch Med, Dept Resp Med, Tokyo, Japan
关键词
miliary tuberculosis; hemophagocytic syndrome; noncaseating epithelioid granulomatous inflammation; RESPIRATORY-DISTRESS-SYNDROME; LYMPHOHISTIOCYTOSIS; CORTICOSTEROIDS;
D O I
10.2169/internalmedicine.56.8025
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We herein report a rare case of miliary tuberculosis-associated hemophagocytic syndrome (HPS) complicated with respiratory failure. A 19-year-old Japanese woman with a fever, general malaise, and chest radiograph abnormalities was referred to our hospital. After admission, she developed respiratory failure with pancytopenia. A histological examination of lung and bone marrow biopsy samples revealed noncaseating granulomas without evidence of acid-fast bacilli or lymphoma. In addition, a bone marrow biopsy showed marked histiocyte hyperplasia with hemophagocytosis, and a bronchoalveolar lavage fluid culture grew Mycobacterium tuberculosis. Therefore, a diagnosis of miliary tuberculosis-associated HPS was made. The patient was successfully treated with antituberculous therapy.
引用
收藏
页码:1591 / 1596
页数:6
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