Blapidly rising prevalence of nosocomial multidrug-resistant, gram-negative bacilli: A 9-year surveillance study

被引：88

作者：

D'Agata, EMC ^{[1
]}

机构：

[1] Harvard Univ, Div Infect Dis, Sch Med, Div Infect Dis, Boston, MA 02215 USA

来源：

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY | 2004年 / 25卷 / 10期

关键词：

D O I：

10.1086/502306

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

OBJECTIVE: To examine and quantify the temporal trends of nosocomial multidrug-resistant, gram-negative bacilli. DESIGN: A 9-year surveillance study was conducted. Multidrug resistance was defined as resistance to 3 or more antimicrobial classes. SETTING: Tertiary-care institution. RESULTS: From 1994 to 2002, multi drug-resistant, gram-negative bacilli increased from 1% to 16% for multidrug-resistant Pseudomonas aeruginosa, 4% to 13% for multidrug-resistant Enterobacter species, 0.5% to 17% for multidrug-resistant Klebsiella species, 0% to 9% for multidrug-resistant Proteus species, and 0.2% to 4% for multidrug-resistant Escherichia coli (P less than or equal to .05). The most common pattern of multidrug resistance was co-resistance to quinolones, third-generation cephalosporins, and aminoglycosides. CONCLUSION: The rapid rise of multidrug-resistant, gram-negative bacilli may warrant infection control programs to include these pathogens in strategies aimed at limiting the emergence and spread of antimicrobial-resistant pathogens.

引用

页码：842 / 846

页数：5

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