Cell manipulation using magnetic nanowires

被引:189
作者
Hultgren, A [1 ]
Tanase, M
Chen, CS
Meyer, GJ
Reich, DH
机构
[1] Johns Hopkins Univ, Dept Phys & Astron, Baltimore, MD 21218 USA
[2] Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD 21218 USA
[3] Johns Hopkins Univ, Dept Chem, Baltimore, MD 21218 USA
[4] Johns Hopkins Univ, Dept Mat Sci & Engn, Baltimore, MD 21218 USA
关键词
D O I
10.1063/1.1556204
中图分类号
O59 [应用物理学];
学科分类号
摘要
The use of magnetic nanowires is demonstrated as a method for the application of force to mammalian cells. Magnetic separations were carried out on populations of NIH-3T3 mouse fibroblast cells using ferromagnetic Ni wires 350 nm in diameter and 35 mum long. Separation purities in excess of 90% and yields of 49% are obtained. The nanowires are shown to outperform magnetic beads of comparable volume. (C) 2003 American Institute of Physics.
引用
收藏
页码:7554 / 7556
页数:3
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