Hormonal preservation of bone in rheumatoid arthritis

被引：3
作者：
Bijlsma, JWJ [1 ]
Jacobs, JWG [1 ]
机构：
[1] Univ Utrecht, Med Ctr, Dept Rheumatol & Clin Immunol, NL-3508 GA Utrecht, Netherlands
来源：
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2000年 / 26卷 / 04期
关键词：
D O I：
10.1016/S0889-857X(05)70175-7
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Generalized as well as localized (periarticular) bone loss is a hallmark of rheumatoid arthritis (RA), leading to an increased fracture risk of 1.5 to 2.1. When patients with RA are being treated with glucocorticoids, this fracture risk doubles again. Factors involved are rheumatoid arthritis specific such as the influence of disease activity, deficient sex hormone status, and more general mechanisms such as due to the use of glucocorticoids.
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页码：897 / +
页数：15
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