Interventions to reduce the risk of ovarian and fallopian tube cancer: A European Menopause and Andropause Society Position Statement

被引：11

作者：

Perez-Lopez, Faustino R. ^{[1
]}

Ceausu, Iuliana ^{[2
,3
]}

Depypere, Herman ^{[4
,5
]}

Kehoe, Sean ^{[6
]}

Lambrinoudaki, Irene ^{[7
]}

Mueck, Alfred ^{[8
]}

Senturk, Levent M. ^{[9
]}

Simoncini, Tommaso ^{[10
]}

Stevenson, John C. ^{[11
]}

Stute, Petra ^{[12
]}

Rees, Margaret ^{[13
]}

机构：

[1] Zaragoza Univ, Lozano Blesa Univ Hosp, Dept Obstet & Gynecol, Fac Med, Zaragoza 50009, Spain

[2] Carol Davila Univ Med & Pharm, Dept Obstet & Gynecol, Bucharest, Romania

[3] Dr I Cantacuzino Hosp, Dept Obstet & Gynecol, Bucharest, Romania

[4] Univ Hosp, Breast Clin, De Pintelaan 185, B-9000 Ghent, Belgium

[5] Univ Hosp, Menopause Clin, De Pintelaan 185, B-9000 Ghent, Belgium

[6] Univ Birmingham, Inst Canc & Genom, Lawson Tait Prof Gynaecol Canc, Birmingham, W Midlands, England

[7] Natl & Kapodestrian Univ Athens, Dept Obstet & Gynecol 2, Athens, Greece

[8] Univ Womens Hosp Tuebingen, Calwer St 7, D-72076 Tubingen, Germany

[9] Istanbul Univ, Cerrahpasa Sch Med, Dept Obstet & Gynecol, Div Reprod Endocrinol,IVF Unit, Istanbul, Turkey

[10] Univ Pisa, Dept Clin & Expt Med, Via Roma 67, I-56100 Pisa, Italy

[11] Imperial Coll London, Royal Brompton Hosp, Natl Heart & Lung Inst, London SW3 6NP, England

[12] Univ Womens Hosp, Dept Obstet & Gynecol, Bern, Switzerland

[13] John Radcliffe Hosp, Womens Ctr, Oxford OX3 9DU, England

来源：

MATURITAS | 2017年 / 100卷

关键词：

Ovarian cancer; Fallopian tubes cancer; Ovarian borderline tumors; BRCA gene mutation; Bilateral salpingectomy; Bilateral oophorectomy; Combined oral contraceptives; Hysterectomy; Non-steroid anti-inflammatory drugs; Obesity; Smoking; PELVIC-INFLAMMATORY-DISEASE; ORAL-CONTRACEPTIVE USE; SALPINGO-OOPHORECTOMY; HORMONE-THERAPY; ENDOMETRIAL CANCER; GYNECOLOGIC CANCER; HEREDITARY BREAST; CIGARETTE-SMOKING; WOMEN; BORDERLINE;

D O I：

10.1016/j.maturitas.2017.03.003

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Background: Ovarian cancer is a leading cause of female gynecological cancer-related death, and there are no effective screening procedures or early diagnostic approaches. Aims: To examine risk factors and risk-reducing strategies for both sporadic and familial tumors. Materials and methods: Literature review and consensus of expert opinion. Results and conclusions: In women with a genetic predisposition to ovarian cancer, salpingo-oophorectomy reduces the risk of ovarian malignancy, and to a lesser degree of breast cancer. Opportunistic bilateral salpingo-oophorectomy and bilateral salpingectomy may also prevent epithelial ovarian cancer. In premenopausal women, bilateral salpingectomy should be preferred to tubal ligation, and be performed when hysterectomy is carried out for benign uterine disease. Hysterectomy and the use of combined oral contraceptives and non-steroid anti-inflammatory drugs are also recognized to reduce the risk of ovarian cancer, as do the prevention of obesity and smoking cessation. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：86 / 91

页数：6

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