Nitroxide radical-modified CuS nanoparticles for CT/MRI imaging-guided NIR-II laser responsive photothermal cancer therapy

被引：4
作者：
Xia, Chengwan [1 ]
Xie, Diya [1 ]
Xiong, Lang [1 ]
Zhang, Qian [1 ]
Wang, Yang [1 ]
Wang, Zezheng [1 ]
Wang, Yuxin [1 ]
Li, Bin [1 ]
Zhang, Chao [1 ,2 ]
机构：
[1] Nanjing Univ, Nanjing Stomatol Hosp, Med Sch, Nanjing 210093, Jiangsu, Peoples R China
[2] Nanjing Univ, Collaborat Innovat Ctr Chem Life Sci, Coll Engn & Appl Sci, Nanjing 210093, Jiangsu, Peoples R China
来源：
RSC ADVANCES | 2018年 / 8卷 / 48期
关键词：
MICROENVIRONMENTAL REGULATION; COMPUTED-TOMOGRAPHY; GOLD NANOPARTICLES; GENE TRANSFECTION; CONTRAST AGENTS; DRUG-DELIVERY; CHEMOTHERAPY; GRAPHENE; OXIDE; STERILIZATION;
D O I：
10.1039/c8ra04501a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, we reported nitroxide radical-modified CuS nanoparticles (CuS-NO center dot NPs), and they exhibited a typical absorption peak at 1182 nm. Due to such a long wavelength absorbance, CuS-NO center dot NPs exhibited excellent therapeutic outcome and low damage to normal tissues. Besides, we simultaneously achieved CuS-NO center dot NPs for MRI and CT dual-modal imaging, which successfully provided a new strategy for imaging-guided tumor treatment, thus increasing potential clinical applications for cancer treatment.
引用
收藏
页码：27382 / 27389
页数：8
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