Vascular-specific growth factors and blood vessel formation

被引：3087

作者：

Yancopoulos, GD ^{[1
]}

Davis, S ^{[1
]}

Gale, NW ^{[1
]}

Rudge, JS ^{[1
]}

Wiegand, SJ ^{[1
]}

Holash, J ^{[1
]}

机构：

[1] Regeneron Pharmaceut Inc, Tarrytown, NY 10591 USA

来源：

NATURE | 2000年 / 407卷 / 6801期

关键词：

D O I：

10.1038/35025215

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A recent explosion in newly discovered vascular growth factors has coincided with exploitation of powerful new genetic approaches for studying vascular development. An emerging rule is that all of these factors must be used in perfect harmony to form functional vessels. These new findings also demand re-evaluation of therapeutic efforts aimed at regulating blood vessel growth in ischaemia, cancer and other pathological settings.

引用

页码：242 / 248

页数：7

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