Idiopathic Intracranial Hypertension in Monozygotic Female Twins: Intracranial Pressure Dynamics and Treatment Outcome

被引:7
作者
Polemikos, Manolis [1 ]
Heissler, Hans E. [1 ]
Hermann, Elvis J. [1 ]
Krauss, Joachim K. [1 ]
机构
[1] Hannover Med Sch, Dept Neurosurg, Hannover, Germany
关键词
Familial; Idiopathic intracranial hypertension; Intracranial pressure; Monozygotic twins; Pseudotumor cerebri; PSEUDOTUMOR CEREBRI; INTRAVENTRICULAR CATHETERS; ELECTROMAGNETIC NAVIGATION; DIAGNOSTIC-CRITERIA; PAPILLEDEMA; PLACEMENT; SAFETY;
D O I
10.1016/j.wneu.2017.03.004
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND: Familial cases of idiopathic intracranial hypertension (IIH) are exceedingly rare, and its occurrence in monozygotic twins has not been reported previously. CASE DESCRIPTION: We report monozygotic female twins who developed IIH, one at age 25 years and the other at age 28 years. Continuous intracranial pressure (ICP) monitoring confirmed elevated ICP as measured initially by lumbar puncture. In both cases, successful treatment with resolution of papilledema and symptoms relief was achieved after ventriculoperitoneal shunting. CONCLUSIONS: This report documents the first case of IIH in monozygotic twins and the associated changes in ICP dynamics. Interestingly, almost equivalent alterations in ICP dynamics were found in the 2 patients.
引用
收藏
页码:814.e11 / 814.e14
页数:4
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