The impact of HIV on naive T-cell homeostasis

被引:43
作者
Grossman, Z [1 ]
Paul, WE
机构
[1] Tel Aviv Univ, Sackler Fac Med, Dept Physiol & Pharmacol, IL-69978 Tel Aviv, Israel
[2] NIAID, Immunol Lab, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1038/79667
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Correlational data and mathematical modeling suggest that increased division rate of naive T cells, not reduced thymic output, lowers the frequency of original thymic emigration among these cells in HIV infected individuals. But are there alternate explanations for these data? (pages 1036-1042). © 2000 Nature America Inc.
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收藏
页码:976 / 977
页数:2
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