The ProDom database of protein domain families

被引:171
作者
Corpet, F
Gouzy, J
Kahn, D
机构
[1] INRA, CNRS, Lab Genet Cellulaire, F-31326 Castanet Tolosan, France
[2] INRA, CNRS, Lab Biol Mol Relat Plantes Microorganismes, F-31326 Castanet Tolosan, France
关键词
D O I
10.1093/nar/26.1.323
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The ProDom database contains protein domain families generated from the SWISS-PROT database by automated sequence comparisons. It can be searched on the World Wide Web (http://protein.toulouse.inra.fr/prodom.html) or by E-mail (prodom@toulouse.inra.fr) to study domain arrangements within known families or new proteins. Strong emphasis has been put on the graphical user interface which allows for interactive analysis of protein homology relationships. Recent improvements to the sewer include: ProDom search by keyword; links to PROSITE and PDB entries; more sensitive ProDom similarity search with BLAST or WU-BLAST; alignments of query sequences with homologous ProDom domain families; and links to the SWISS-MODEL server (http://www.expasy.ch/swissmod/SWISS-MODEL.html) for homology based 3-D domain modelling where possible.
引用
收藏
页码:323 / 326
页数:4
相关论文
共 20 条
  • [1] ABOLA EE, 1987, CRYSTALLOGRAPHIC DAT, P107
  • [2] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
    Altschul, SF
    Madden, TL
    Schaffer, AA
    Zhang, JH
    Zhang, Z
    Miller, W
    Lipman, DJ
    [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (17) : 3389 - 3402
  • [3] BASIC LOCAL ALIGNMENT SEARCH TOOL
    ALTSCHUL, SF
    GISH, W
    MILLER, W
    MYERS, EW
    LIPMAN, DJ
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) : 403 - 410
  • [4] A NEW-GENERATION OF INFORMATION-RETRIEVAL TOOLS FOR BIOLOGISTS - THE EXAMPLE OF THE EXPASY WWW SERVER
    APPEL, RD
    BAIROCH, A
    HOCHSTRASSER, DF
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1994, 19 (06) : 258 - 260
  • [5] ATWOOD TK, 1998, NUCLEIC ACIDS RES, V26, P168
  • [6] ATWOOD TK, 1997, NUCLEIC ACIDS RES, V25, P217
  • [7] ATWOOD TK, 1997, NUCLEIC ACIDS RES, V25, P212
  • [8] The SWISS-PROT protein sequence data bank and its supplement TrEMBL
    Bairoch, A
    Apweller, R
    [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (01) : 31 - 36
  • [9] The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1998
    Bairoch, A
    Apweiler, R
    [J]. NUCLEIC ACIDS RESEARCH, 1998, 26 (01) : 38 - 42
  • [10] MULTIPLE SEQUENCE ALIGNMENT WITH HIERARCHICAL-CLUSTERING
    CORPET, F
    [J]. NUCLEIC ACIDS RESEARCH, 1988, 16 (22) : 10881 - 10890