International Multicenter Trial on Clinical Natural Orifice Surgery-NOTES IMTN Study: Preliminary Results of 362 Patients

被引：139

作者：

Zorron, Ricardo ^{[1
]}

Palanivelu, Chinnusamy ^{[2
]}

Galvao Neto, Manoel Passos ^{[3
]}

Ramos, Almino ^{[3
]}

Salinas, Gustavo ^{[4
]}

Burghardt, Jens ^{[5
]}

DeCarli, Luis ^{[6
]}

Sousa, Luiz Henrique ^{[7
]}

Forgione, Antonello ^{[8
,17
]}

Pugliese, Raffaele ^{[8
,17
]}

Branco, Alcides J. ^{[9
]}

Balashanmugan, T. S. ^{[10
]}

Boza, Camilo ^{[11
]}

Corcione, Francesco ^{[12
]}

D'Avila Avila, Fausto ^{[13
]}

Arturo Gomez, Nestor ^{[14
]}

Galvao Ribeiro, Paulo Ayrosa ^{[3
]}

Martins, Susana

Filgueiras, Marcos

Gellert, Klaus ^{[5
]}

Branco, Anibal Wood ^{[9
]}

Kondo, William ^{[9
]}

Sanseverino, Jose Inacio ^{[6
]}

de Sousa, Jose Americo G. ^{[7
]}

Saavedra, Lil ^{[4
]}

Ramirez, Edwin ^{[4
]}

Campos, Josemberg ^{[15
]}

Sivakumar, K. ^{[10
]}

Rajan, Pidigu Seshiyer ^{[2
]}

Jategaonkar, Priyadarshan Anand ^{[2
]}

Ranagrajan, Muthukumaran ^{[2
]}

Parthasarathi, Ramakrishnan ^{[2
]}

Senthilnathan, Palanisamy ^{[2
]}

Prasad, Mohan ^{[2
]}

Cuccurullo, Diego ^{[16
]}

Mueller, Verena ^{[5
]}

机构：

[1] Univ Hosp Teresopolis HCTCO FESO, Dept Surg, NOTES Res Grp, Rio De Janeiro, Brazil

[2] GEM Hosp & Postgrad Inst, Coimbatore, Tamil Nadu, India

[3] Hosp Santa Rita, Sao Paulo, Brazil

[4] Clin Dia Avendano, Lima, Peru

[5] Sana Clin Ctr Berlin, Berlin, Germany

[6] Hosp Irmandade Santa Casa Misericordia, Porto Alegre, RS, Brazil

[7] SOUSAGRP Hosp Femina, Goiania, Go, Brazil

[8] Osped Niguarda Ca Granda, Milan, Italy

[9] Cruz Vermelha Hosp Curitiba, BR-80420011 Curitiba, Parana, Brazil

[10] PSG Hosp, Coimbatore, Tamil Nadu, India

[11] Pontificia Univ Catolica Chile, Santiago, Chile

[12] Hosp UOC Gen & Laparoscop Surg, Naples, Italy

[13] Hosp Poza Rica, Poza Rica, Mexico

[14] Univ Guayaquil, Guayaquil, Ecuador

[15] Univ Recife, Recife, PE, Brazil

[16] NOC Chirugia Gen & Laparoscop, Naples, Italy

[17] Adv Int Mini Invas Surg Acad, Milan, Italy

来源：

SURGICAL INNOVATION | 2010年 / 17卷 / 02期

关键词：

natural orifice surgery; NOTES; laparoscopy; minimally invasive surgery; natural orifice translumenal endoscopic surgery; prospective study; multicenter study; cholecystectomy; appendectomy; TRANSLUMENAL ENDOSCOPIC SURGERY; NOTES TRANSVAGINAL CHOLECYSTECTOMY; LAPAROSCOPIC CHOLECYSTECTOMY; TRANSGASTRIC SURGERY; PORCINE MODEL; TRANSESOPHAGEAL MEDIASTINOSCOPY; INITIAL-EXPERIENCE; HYBRID APPROACH; SURVIVAL; APPENDECTOMY;

D O I：

10.1177/1553350610370968

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Objectives: Natural orifice translumenal endoscopic surgery (NOTES) is evolving as a promising alternative for abdominal surgery. IMTN Registry was designed to prospectively document early results of natural orifice surgery among a large group of clinical cases. Methods: Sixteen centers from 9 countries were approved to participate in the study, based on study protocol requirements and local institutional review board approval. Transgastric and transvaginal endoscopic natural orifice surgery was clinically applied in 362 patients. Intraoperative and postoperative parameters were prospectively documented. Results: Mean operative time for transvaginal cholecystectomy was 96 minutes, compared with 111 minute for transgastric cholecystectomy. A general complication rate of 8.84% was recorded (grade I-II representing 5.8%, grade III-IV representing 3.04%). No requirement for any analgesia was found in one fourth of cholecystectomy and appendectomy patients. Conclusions: Results of clinical applications of NOTES in the IMTN Study showed the feasibility of different methods of this new minimally invasive alternative for laparoscopic and open surgery.

引用

页码：142 / 158

页数：17