Short-term effectiveness of HIV care coordination among persons with recent HIV diagnosis or history of poor HIV outcomes

被引:20
作者
Nash, Denis [1 ,2 ]
Robertson, McKaylee M. [1 ,2 ]
Penrose, Kate [3 ]
Chamberlin, Stephanie [3 ]
Robbins, Rebekkah S. [3 ]
Braunstein, Sarah L. [3 ]
Myer, Julie E. [3 ,4 ]
Abraham, Bisrat [3 ]
Kulkarni, Sarah [1 ,2 ]
Waldron, Levi [1 ,2 ]
Levin, Bruce [5 ]
Irvine, Mary K. [3 ]
机构
[1] CUNY, Inst Implementat Sci Populat Hlth, New York, NY 10021 USA
[2] CUNY, Grad Sch Publ Hlth & Hlth Policy, New York, NY 10021 USA
[3] New York City Dept Hlth & Mental Hyg, Bur HIV AIDS, New York, NY USA
[4] Columbia Univ Coll Phys & Surg, Div Infect Dis, Dept Med, 630 W 168th St, New York, NY 10032 USA
[5] Columbia Univ, Mailman Sch Publ Hlth, Dept Biostat, New York, NY USA
基金
美国国家卫生研究院;
关键词
VIRAL LOAD SUPPRESSION; NEW-YORK-CITY; CASE-MANAGEMENT; ANCILLARY SERVICES; INFECTED PERSONS; RANDOMIZED-TRIAL; HOUSING STATUS; UNITED-STATES; MEDICAL-CARE; RETENTION;
D O I
10.1371/journal.pone.0204017
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The New York City HIV Care Coordination Program (CCP) combines multiple evidence-based strategies to support persons living with HIV (PLWH) at risk for, or with a recent history of, poor HIV outcomes. We assessed the comparative effectiveness of the CCP by merging programmatic data on CCP clients with population-based surveillance data on all New York City PLWH. A non-CCP comparison group of similar PLWH who met CCP eligibility criteria was identified using surveillance data. The CCP and non-CCP groups were matched on propensity for CCP enrollment within four baseline treatment status groups (newly diagnosed or previously diagnosed and either consistently unsuppressed, inconsistently suppressed or consistently suppressed). We compared CCP to non-CCP proportions with viral load suppression at 12-month follow-up. Among the 13,624 persons included, 15.3% were newly diagnosed; among the 84.7% previously diagnosed, 14.2% were consistently suppressed, 28.9% were inconsistently suppressed, and 41.6% were consistently unsuppressed in the year prior to baseline. At 12-month follow-up, 59.9% of CCP and 53.9% of non-CCP participants had viral load suppression (Relative Risk = 1.11, 95% CI:1.08-1.14). Among those newly diagnosed and those consistently unsuppressed at baseline, the relative risk of viral load suppression in the CCP versus non-CCP participants was 1.15 (95%CI:1.09-1.23) and 1.32 (95%CI:1.23-1.42), respectively. CCP exposure shows benefits over no CCP exposure for persons newly diagnosed or consistently unsuppressed, but not for persons suppressed in the year prior to baseline. We recommend more targeted case finding for CCP enrollment and increased attention to viral load suppression maintenance.
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页数:14
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