Perspectives on the development and future of oocyte IVM in clinical practice

被引:124
作者
De Vos, Michel [1 ,2 ]
Grynberg, Michael [3 ,4 ]
Ho, Tuong M. [5 ]
Yuan, Ye [6 ]
Albertini, David F. [7 ]
Gilchrist, Robert B. [8 ]
机构
[1] UZ Brussel, Ctr Reprod Med, Brussels, Belgium
[2] Sechenov Univ, Inst Profess Educ, Dept Obstet Gynecol Perinatol & Reproductol, Moscow, Russia
[3] Antoine Beclere Univ Hosp, Dept Reprod Med & Fertil Preservat, Clamart, France
[4] Paris Sud Univ, Le Kremlin Bicetre, France
[5] My Duc Hosp, IVFMD, Ho Chi Minh City, Vietnam
[6] Colorado Ctr Reprod Med, Lone Tree, CO 80124 USA
[7] Bedford Res Fdn, 124 South Rd, Bedford, MA 01730 USA
[8] Univ New South Wales Sydney, Sch Womens & Childrens Hlth, Fertil & Res Ctr, Sydney, NSW, Australia
基金
英国医学研究理事会;
关键词
In vitro maturation (IVM); Oocyte maturation; Onco-fertility; Fertility preservation; Polycystic ovary syndrome (PCOS); IN-VITRO MATURATION; OVARIAN HYPERSTIMULATION SYNDROME; HUMAN CHORIONIC-GONADOTROPIN; HORMONE RECEPTOR GENE; ASSISTED REPRODUCTIVE TECHNOLOGY; FROZEN-EMBRYO-TRANSFER; ANTRAL FOLLICLE COUNT; FERTILITY PRESERVATION; POLYCYSTIC OVARIES; COMPARATIVE BEHAVIOR;
D O I
10.1007/s10815-021-02263-5
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Oocyte in vitro maturation (IVM) is an assisted reproductive technology designed to obtain mature oocytes following culture of immature cumulus-oocyte complexes collected from antral follicles. Although IVM has been practiced for decades and is no longer considered experimental, the uptake of IVM in clinical practice is currently limited. The purpose of this review is to ensure reproductive medicine professionals understand the appropriate use of IVM drawn from the best available evidence supporting its clinical potential and safety in selected patient groups. This group of scientists and fertility specialists, with expertise in IVM in the ART laboratory and/or clinic, explore here the development of IVM towards acquisition of a non-experimental status and, in addition, critically appraise the current and future role of IVM in human ART.
引用
收藏
页码:1265 / 1280
页数:16
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