Lung Allograft Rejection

被引：8
作者：
Levine, Deborah J. [1 ]
Hachem, Ramsey R. [2 ]
机构：
[1] Univ Texas Hlth San Antonio, Div Pulm & Crit Care Med, 7703 Floyd Curl Dr, San Antonio, TX 78229 USA
[2] Washington Univ, Div Pulm & Crit Care Med, 4523 Clayton Ave,Mailstop 8052-0043-14, St Louis, MO 63110 USA
来源：
THORACIC SURGERY CLINICS | 2022年 / 32卷 / 02期
关键词：
Lung transplantation; Acute cellular rejection; Antibody-mediated rejection; Donor-specific antibodies; ANTIBODY-MEDIATED REJECTION; ACUTE CELLULAR REJECTION; BRONCHIOLITIS OBLITERANS SYNDROME; REFRACTORY ACUTE REJECTION; DONOR-SPECIFIC ANTIBODIES; HLA-SPECIFIC ANTIBODIES; HYPERACUTE REJECTION; CONTROLLED-TRIAL; PLASMA-EXCHANGE; HEART-LUNG;
D O I：
10.1016/j.thorsurg.2021.12.003
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Rejection is a major complication following lung transplantation. Acute cellular rejection (ACR), and antibody-mediated rejection (AMR) are risk factors for the subsequent development of chronic lung allograft dysfunction and worse outcomes after transplantation. Although ACR has well-defined histopathologic diagnostic criteria and grading, the diagnosis of AMR requires a multidisciplinary diagnostic approach. This article reviews the identification, clinical and pathologic features of, and therapeutic options for ACR and AMR. Copyright © 2021 Elsevier Inc. All rights reserved.
引用
收藏
页码：221 / 229
页数：9
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